Publications

2020

  1. Lee HM, Kuijer MB, Ruiz Blanes N, Clark EP, Aita M, Galiano Arjona L, Kokot A, Sciaky N, Simon JM, Bhatnagar S, Philpot BD, Cerase A. A small-molecule screen reveals novel modulators of MeCP2 and X-chromosome inactivation maintenance. J Neurodev Disord. 2020 Nov 10;12(1):29. doi: 10.1186/s11689-020-09332-3. PubMed PMID: 33172406; PubMed Central PMCID: PMC7657357.
  2. Przanowski P, Lou S, Tihagam RD, Mondal T, Conlan C, Shivange G, Saltani I, Singh C, Xing K, Morris BB, Mayo MW, Teixeira L, Lehmann-Che J, Tushir-Singh J, Bhatnagar S. Oncogenic TRIM37 Links Chemoresistance and Metastatic Fate in Triple-Negative Breast Cancer. Cancer Res. 2020 Nov 1;80(21):4791-4804. doi: 10.1158/0008-5472.CAN-20-1459. Epub 2020 Aug 27. PubMed PMID: 32855208; PubMed Central PMCID: PMC7731897.
  3. Przanowska RK, Sobierajska E, Su Z, Jensen K, Przanowski P, Nagdas S, Kashatus JA, Kashatus DF, Bhatnagar S, Lukens JR, Dutta A. miR-206 family is important for mitochondrial and muscle function, but not essential for myogenesis in vitro. FASEB J. 2020 Jun;34(6):7687-7702. doi: 10.1096/fj.201902855RR. Epub 2020 Apr 11. PubMed PMID: 32277852; PubMed Central PMCID: PMC7427345.


2019

  1. Przanowski P, Zheng Z, Wasko U, Bhatnagar S. A Non-random Mouse Model for Pharmacological Reactivation of Mecp2 on the Inactive X Chromosome. J Vis Exp. 2019 May 22;(147). doi: 10.3791/59449. PubMed PMID: 31180354.
  2. Bhatnagar S, Tushir-Singh J. Targeting HER2 beyond breast cancer. Mol Cell Oncol. 2019;6(3):1571984. doi: 10.1080/23723556.2019.1571984. eCollection 2019. PubMed PMID: 31131305; PubMed Central PMCID: PMC6512921.
  3. Waśko U, Zheng Z, Bhatnagar S. Visualization of Xist Long Noncoding RNA with a Fluorescent CRISPR/Cas9 System. Methods Mol Biol.2019;1870:41-50. doi: 10.1007/978-1-4939-8808-2_3. PubMed PMID: 30539545.


2018

  1. Shivange G, Urbanek K, Przanowski P, Perry JSA, Jones J, Haggart R, Kostka C, Patki T, Stelow E, Petrova Y, Llaneza D, Mayo M, Ravichandran KS, Landen CN, Bhatnagar S, Tushir-Singh J. A Single-Agent Dual-Specificity Targeting of FOLR1 and DR5 as an Effective Strategy for Ovarian Cancer.Cancer Cell. 2018 Aug 13;34(2):331-345.e11. doi: 10.1016/j.ccell.2018.07.005. PubMed PMID: 30107179; PubMed Central PMCID: PMC6404966.
  2. Przanowski P, Wasko U, Zheng Z, Yu J, Sherman R, Zhu LJ, McConnell MJ, Tushir-Singh J, Green MR, Bhatnagar S. Pharmacological reactivation of inactive X-linked Mecp2 in cerebral cortical neurons of living mice. Proc Natl Acad Sci U S A. 2018 Jul 31;115(31):7991-7996. doi: 10.1073/pnas.1803792115. Epub 2018 Jul 16. PubMed PMID: 30012595; PubMed Central PMCID: PMC6077728.
  3. Venkatesan AM, Vyas R, Gramann AK, Dresser K, Gujja S, Bhatnagar S, Chhangawala S, Gomes CBF, Xi HS, Lian CG, Houvras Y, Edwards YJK, Deng A, Green M, Ceol CJ. Ligand-activated BMP signaling inhibits cell differentiation and death to promote melanoma. J Clin Invest. 2018 Jan 2;128(1):294-308. doi: 10.1172/JCI92513. Epub 2017 Dec 4. PubMed PMID: 29202482; PubMed Central PMCID: PMC5749509.


2015-2005

  1. Bhatnagar S, Green MR. TRIMming down tumor suppressors in breast cancer. Cell Cycle. 2015;14(9):1345-6. doi: 10.1080/15384101.2015.1024584. PubMed PMID: 25790001; PubMed Central PMCID: PMC4615100.
  2. Bhatnagar S, Gazin C, Chamberlain L, Ou J, Zhu X, Tushir JS, Virbasius CM, Lin L, Zhu LJ, Wajapeyee N, Green MR. TRIM37 is a new histone H2A ubiquitin ligase and breast cancer oncoprotein. Nature. 2014 Dec 4;516(7529):116-20. doi: 10.1038/nature13955. Epub 2014 Nov 24. PubMed PMID: 25470042; PubMed Central PMCID: PMC4269325.
  3. Bhatnagar S, Zhu X, Ou J, Lin L, Chamberlain L, Zhu LJ, Wajapeyee N, Green MR. Genetic and pharmacological reactivation of the mammalian inactive X chromosome. Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):12591-8. doi: 10.1073/pnas.1413620111. Epub 2014 Aug 18. PubMed PMID: 25136103; PubMed Central PMCID: PMC4156765.
  4. Schorey JS, Bhatnagar S. Exosome function: from tumor immunology to pathogen biology. Traffic. 2008 Jun;9(6):871-81. doi: 10.1111/j.1600-0854.2008.00734.x. Epub 2008 Mar 6. Review. PubMed PMID: 18331451; PubMed Central PMCID: PMC3636814.
  5. Bhatnagar S, Shinagawa K, Castellino FJ, Schorey JS. Exosomes released from macrophages infected with intracellular pathogens stimulate a proinflammatory response in vitro and in vivo. Blood. 2007 Nov 1;110(9):3234-44. doi: 10.1182/blood-2007-03-079152. Epub 2007 Jul 31. PubMed PMID: 17666571; PubMed Central PMCID: PMC2200902.
  6. Bhatnagar S, Schorey JS. Exosomes released from infected macrophages contain Mycobacterium avium glycopeptidolipids and are proinflammatory. J Biol Chem. 2007 Aug 31;282(35):25779-89. doi: 10.1074/jbc.M702277200. Epub 2007 Jun 25. PubMed PMID: 17591775; PubMed Central PMCID: PMC3636815.
  7. Bhatnagar S, Schorey JS. Elevated mitogen-activated protein kinase signalling and increased macrophage activation in cells infected with a glycopeptidolipid-deficient Mycobacterium avium. Cell Microbiol. 2006 Jan;8(1):85-96. doi: 10.1111/j.1462-5822.2005.00602.x. PubMed PMID: 16367868.
  8. Krzywinska E, Bhatnagar S, Sweet L, Chatterjee D, Schorey JS. Mycobacterium avium 104 deleted of the methyltransferase D gene by allelic replacement lacks serotype-specific glycopeptidolipids and shows attenuated virulence in mice. Mol Microbiol. 2005 Jun;56(5):1262-73. doi: 10.1111/j.1365-2958.2005.04608.x. PubMed PMID: 15882419.
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